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CIPN afflicts between 30% and 40% of patients undergoing chemotherapy. Antineoplastic agents in chemotherapy are designed to eliminate rapidly dividing cancer cells, but they can also damage healthy structures, including the peripheral nervous system. [1] CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2]
Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Peripheral neuropathy, often shortened to neuropathy, refers to damage or disease affecting the nerves. [1] Damage to nerves may impair sensation, movement, gland function, and/or organ function depending on which nerve fibers are affected. Neuropathies affecting motor, sensory, or autonomic nerve fibers result in different symptoms. More than ...
A study found that physical exercise can help chemotherapy-induced chronic pain and balance issues caused by nerve damage in people undergoing the cancer ... and less need to adjust medication ...
Neurolysis is the application of physical or chemical agents to a nerve in order to cause a temporary degeneration of targeted nerve fibers. When the nerve fibers degenerate, it causes an interruption in the transmission of nerve signals. In the medical field, this is most commonly and advantageously used to alleviate pain in cancer patients. [1]
Research also shows that lidocaine can help ease nerve pain in people with conditions like diabetes-related nerve damage, complex regional pain syndrome, cancer, and pain after breast surgery.
Dysesthesia, along with polyneuropathy can be a symptom of nerve damage caused by Lyme disease. [4] The dysesthetic sensations continue after the successful antibiotic treatment of Lyme disease. Dysesthesia is a common symptom of a withdrawal from alcohol or other drugs. Dysesthesia is also a common symptom of multiple sclerosis. It is an ...
Existing treatments aim to suppress the immune system to prevent further damage to nerve cells. A new study has developed a treatment that can help regenerate myelin with the potential to stop and ...