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[2]: 599 These tumors were reclassified by Dr. Weiss in 1996 as "spindle cell hemangioma", rather than hemangioendothelioma, due to the excellent prognosis observed in a group of 78 patients. [ 5 ] Retiform hemangioendothelioma (also known as a "Hobnail hemangioendothelioma" [ 3 ] ) is a low-grade angiosarcoma , first described in 1994 ...
Hemangiopericytomas are tumors that are derived from specialized spindle shaped cells called pericytes, which line capillaries. [4] Hemangiopericytoma is an aggressive mesenchymally derived tumor with oval nuclei with scant cytoplasm. There is dense intercellular reticulin staining. Tumor cells can be fibroblastic, myxoid, or pericytic. These ...
Intravascular papillary endothelial hyperplasia typically manifest as deep nodules or well-defined, round, red, or purple superficial papules.They are usually tiny, ranging in size from 0.5 to 5 cm. [3] IPEH lesions are most common in the digits and among blood arteries throughout the body, although they can also form in the head, neck, and body.
Infantile hemangiomas are the most common type of vascular tumor to affect babies, [4] accounting for 90% of hemangiomas. [5] They are characterised by the abnormal proliferation of endothelial cells and of deviant blood vessel formation or architecture. [6] Hypoxic stress seems to be a major trigger for this. [7]
Histologically, microvenular hemangioma is made up of venules with thin walls that branch erratically and have barely noticeable vascular lumina. The dermis's collagen bundles are thickened. [6] Pericytes envelop the endothelial cells, [9] which can exhibit a combination of plump and flat cells without pleomorphism or mitotic patterns. [10]
[13] [12] In interstitial and perivascular spindle cells, as well as rarely in multinucleate cells, estrogen receptor α has significant expression. [7] Angiofibroma/fibrous papule, dermatofibroma, microvenular hemangioma, Kaposi's sarcoma, and acroangiodermatitis are among the histopathologic differential diagnoses. [4]
Cavernous hemangiomas are erroneously called the most common benign tumors of the liver. [14] Usually one malformation exists, but multiple lesions can occur in the left or right lobe of the liver in 40% of patients. [3] Their sizes can range from a few millimeters to 20 centimetres. Those over 5 cm are often referred to as giant hemangiomas. [3]
Angiolymphoid hyperplasia with eosinophilia (also known as: [1] "Epithelioid hemangioma," "Histiocytoid hemangioma," "Inflammatory angiomatous nodule," "Intravenous atypical vascular proliferation," "Papular angioplasia," "Inflammatory arteriovenous hemangioma," and "Pseudopyogenic granuloma") usually presents with pink to red-brown, dome-shaped, dermal papules or nodules of the head or neck ...