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Signs of overdose include exacerbated side effects such as joint pain, swelling, and lameness. [ 4 ] [ 7 ] When dogs received three times the normal dose intramuscularly twice a week for 13 weeks, they had increased liver and kidney weight, as well as microscopic lesions on the liver, kidneys, and lymph nodes .
It is a reasonable initial treatment for high blood pressure. [8] It is taken by mouth. [8] Common side effects include feeling tired, dizziness, high blood potassium, diarrhea, and joint pain. [8] Other serious side effects may include kidney problems, low blood pressure, and angioedema. [8]
Renal dysplasia is a type of familial kidney disease characterized by abnormal cellular differentiation of kidney tissue. Dogs and cats with kidney disease caused by these diseases have the typical symptoms of kidney failure, including weight loss, loss of appetite, depression, and increased water consumption and urination. [ 1 ]
The most obvious cause is a kidney or systemic disorder, including amyloidosis, [2] polycystic kidney disease, [3] electrolyte imbalance, [4] [5] or some other kidney defect. [2] The major causes of acquired nephrogenic diabetes insipidus that produce clinical symptoms (e.g., polyuria) in the adult are lithium toxicity and high blood calcium.
Diagnosis is made by recognizing the combination of symptoms and abnormal blood tests that occur in infectious canine hepatitis. A rising antibody titer to CAV-1 is also seen. The disease can be confused with canine parvovirus because both will cause a low white blood cell count and bloody diarrhea in young, unvaccinated dogs.
Tumors can start in the liver, or spread to the liver from another cancer in the body. Malignant liver tumors have been reported to metastasize to other organs such as regional lymph nodes, lungs, kidneys, pancreas, spleen and others.
In most cases, appropriate treatment protocols cause few side effects, but white blood cell counts must be monitored. Allogeneic and autologous stem cell transplantations (as is commonly done in humans) have recently been shown to be a possible treatment option for dogs. [19] Most of the basic research on transplantation biology was generated ...
pimobendan – phosphodiesterase 3 inhibitor used to manage heart failure in dogs; pirlimycin – antimicrobial; ponazuril – anticoccidial; praziquantel – treatment of infestations of the tapeworms Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus; prazosin – sympatholytic used in hypertension and abnormal muscle contractions