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  2. Bevacizumab - Wikipedia

    en.wikipedia.org/wiki/Bevacizumab

    Bevacizumab, sold under the brand name Avastin among others, is a monoclonal antibody medication used to treat a number of types of cancers and a specific eye disease. [30] [28] For cancer, it is given by slow injection into a vein (intravenous) and used for colon cancer, lung cancer, ovarian cancer, glioblastoma, hepatocellular carcinoma, and renal-cell carcinoma. [31]

  3. Osmotherapy - Wikipedia

    en.wikipedia.org/wiki/Osmotherapy

    Currently, osmotherapy is the only way to reduce cerebral edema, and hypertonic saline appears to be better than other osmotic agents. According to some researchers, glycerol can be best administered as a basal treatment whereas mannitol can be administered to control sudden rises in ICP. [7]

  4. Arachidonate 5-lipoxygenase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Arachidonate_5-lipoxygen...

    Boswellia administration has been shown to reduce brain edema in patients irradiated for brain tumor and it is believed to be due to 5-lipoxygenase inhibition. [ 11 ] [ 12 ] See also

  5. Cerebral edema - Wikipedia

    en.wikipedia.org/wiki/Cerebral_edema

    The Monroe–Kellie doctrine states that the skull is a fixed and inelastic space and the accumulation of edema will compress vital brain tissue and blood vessels. [8] [38] Surgical treatment of cerebral edema in the context of cerebellar or cerebral infarction is typically done by removing part of the skull to allow expansion of the dura. [38]

  6. Monoclonal antibody therapy - Wikipedia

    en.wikipedia.org/wiki/Monoclonal_antibody_therapy

    However, in patients with increased apolipoprotein (APOE) e4 carriers, Bapineuzumab treatment is also accompanied by vasogenic edema, [28] a cytotoxic condition where the blood brain barrier has been disrupted thereby affecting white matter from excess accumulation of fluid from capillaries in intracellular and extracellular spaces of the brain ...

  7. Intracranial pressure - Wikipedia

    en.wikipedia.org/wiki/Intracranial_pressure

    An increase in pressure, most commonly due to head injury leading to intracranial hematoma or cerebral edema, can crush brain tissue, shift brain structures, contribute to hydrocephalus, cause brain herniation, and restrict blood supply to the brain. [13] It is a cause of reflex bradycardia. [14]