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The lesions are most frequent on the lower limbs, but may occur anywhere on the body, including the hands, arms, torso and even the neck. They may vary in number and erupt in mass numbers. They consist of irregular patches of orange or brown pigmentation with characteristic "cayenne pepper" spots appearing within and at the edge of old lesions.
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis . Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair.
The spots derive their name from the fact that they were once incorrectly believed to be caused by liver problems, but they are physiologically unrelated to the liver, save for a similar color. [6] From the age of 40, the skin is less able to regenerate from sun exposure, and liver spots are very common in this age group, particularly in those ...
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Pigmentation disorders are disturbances of human skin color. [1] There may be a loss or reduction, which may be related to loss of melanocytes or the inability of melanocytes to produce melanin or transport melanosomes correctly. [1] Most pigmentation disorders involve the underproduction or overproduction of melanin. [2] [3]
Excessive consumption of elemental silver, silver dust or silver compounds can cause the skin to be colored blue or bluish-grey. This condition is called argyria. A similar skin color can result from prolonged exposure to gold, typically as a little-used medical treatment. The gold-induced greyish skin color is called chrysiasis. Argyria and ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 28 January 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...
The area of skin affected grows in proportion to general growth. Port-wine stains occur most often on the face but can appear anywhere on the body, particularly on the neck, upper trunk, arms and legs. [2] [4] Early stains are usually flat and pink in appearance. As the child matures, the color may deepen to a dark red or purplish color. [2]