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The notochord is an elastic, rod-like structure found in chordates. In chordate vertebrates the notochord is an embryonic structure that disintegrates, as the vertebrae develop, to become the nucleus pulposus in the intervertebral discs of the vertebral column.
The notochord will form the nucleus pulposus of intervertebral discs. There is some discussion as to whether these cells contributed from the notochord are replaced by others from the adjacent mesoderm. It gives rise to the notochordal process, which later becomes the notochord.
The mesoderm is one of the three germinal layers that appears in the third week of embryonic development. It is formed through a process called gastrulation. There are four important components, which are the axial, paraxial, intermediate, and lateral plate mesoderms. The axial mesoderm gives rise to the notochord.
A primary step in organogenesis for chordates is the development of the notochord, which induces the formation of the neural plate, and ultimately the neural tube in vertebrate development. The development of the neural tube will give rise to the brain and spinal cord. [1]
These mesodermal cells that migrate along the dorsal midline give rise to a structure called the notochord. Ectodermal cells overlying the notochord develop into the neural plate in response to a diffusible signal produced by the notochord. The remainder of the ectoderm gives rise to the epidermis (skin).
Mesodermal cells migrate along the dorsal midline to give rise to the notochord that develops into the vertebral column. Neuroectoderm overlying the notochord develops into the neural plate in response to a diffusible signal produced by the notochord. The remainder of the ectoderm gives rise to the epidermis.
The notochord extends from the base of the head to the tail; with it extend thick bands of paraxial mesoderm. [ 3 ] As the primitive streak continues to regress, somites form from the paraxial mesoderm by "budding off" rostrally.
The notochord extends from the base of the head to the tail; with it extend thick bands of paraxial mesoderm. [ 1 ] As the primitive streak continues to regress, somites form from the paraxial mesoderm by "budding off" rostrally as somitomeres , or whorls of paraxial mesoderm cells, compact and separate into discrete bodies.