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Lactase persistence is very high among northern Europeans, especially Irish people. Worldwide, most people are lactase non-persistent, [1] and are affected by varying degrees of lactose intolerance as adults. However, lactase persistence and lactose intolerance can overlap.
This form of lactose intolerance can occur in both infants and lactase persistent adults and is generally reversible. [29] It may be caused by acute gastroenteritis , coeliac disease , Crohn's disease , ulcerative colitis , [ 30 ] chemotherapy , intestinal parasites (such as giardia ), or other environmental causes.
The majority of humans actually follow this protocol as well, and down-regulate lactase production around 3-5 years of age. Interestingly, though, the majority of caucasians, mainly those from northern european background, continue to have elevated lactase activity all the way into adulthood, and so they exhibit “lactase persistence”.
People deficient in lactase or lacking functional lactase may experience the symptoms of lactose intolerance after consuming milk products. [1] Microbial β-galactosidase (often loosely referred to as lactase) can be purchased as a food supplement and is added to milk to produce "lactose-free" milk products.
Many adult humans lack the lactase enzyme, which has the same function as β-galactosidase, so they are not able to properly digest dairy products. β-Galactose is used in such dairy products as yogurt, sour cream, and some cheeses which are treated with the enzyme to break down any lactose before human consumption. In recent years, β ...
Pancrelipases are generally a first line approach in treatment of exocrine pancreatic insufficiency and other digestive disorders, accompanying cystic fibrosis, complicating surgical pancreatectomy, or resulting from chronic pancreatitis. The formulations are generally hard capsules filled with gastro-resistant granules. Pancrelipases and ...