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The IOP is higher during sleep. Efficacy of timolol in lowering IOP during the sleep period may be limited. [16] [17] [18] It is a 5–10× more potent beta blocker than propranolol. Timolol is light-sensitive; it is usually preserved with 0.01% benzalkonium chloride (BAC), but also comes BAC-free.
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
Betaxolol is most commonly ingested orally alone or with other medications for the management of essential hypertension. [4] It is a cardioselective beta blocker, targeting beta-1 adrenergic receptors found in the cardiac muscle.
Like other non-selective beta blockers, levobunolol is contraindicated in patients with airway diseases such as asthma and severe chronic obstructive pulmonary disease (COPD), as well as heart problems such as sinus bradycardia, second- or third-degree atrioventricular block, sick sinus syndrome, and cardiogenic shock.
Benzalkonium chloride is a frequently used preservative in eye drops; typical concentrations range from 0.004% to 0.01%. [17] Stronger concentrations can be caustic [18] and cause irreversible damage to the corneal endothelium. [19] Avoiding the use of benzalkonium chloride solutions while contact lenses are in place is discussed in the literature.
NATO was established on 4 April 1949 via the signing of the North Atlantic Treaty (Washington Treaty). The 12 founding members of the Alliance were: Belgium, Canada, Denmark, France, Iceland, Italy, Luxembourg, the Netherlands, Norway, Portugal, the United Kingdom, and the United States.
Chloroxylenol, also known as para-chloro-meta-xylenol (PCMX), is a chlorine substituted phenol with a white to off-white appearance and a phenolic odor.. The discovery of chloroxylenol was the result of efforts to produce improved antiseptics that began at the end of the 1800s, when scientists gradually realized that more substituted and more lipophilic phenols are less toxic, less irritant ...
Several colonies and dominions adopted the pound as their own currency. These included Australia, Barbados, [76] British West Africa, Cyprus, Fiji, British India, the Irish Free State, Jamaica, New Zealand, South Africa and Southern Rhodesia. Some of these retained parity with sterling throughout their existence (e.g. the South African pound ...