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  2. Tacrolimus - Wikipedia

    en.wikipedia.org/wiki/Tacrolimus

    Side effects can be severe and include infection, cardiac damage, hypertension, blurred vision, liver and kidney problems (tacrolimus nephrotoxicity), [26] hyperkalemia, hypomagnesemia, hyperglycemia, diabetes mellitus, itching, lung damage (sirolimus also causes lung damage), [27] and various neuropsychiatric problems such as loss of appetite ...

  3. Immunosuppressive drug - Wikipedia

    en.wikipedia.org/wiki/Immunosuppressive_drug

    Although it is a structural analogue of tacrolimus, it acts somewhat differently and has different side-effects. Contrary to ciclosporin and tacrolimus, drugs that affect the first phase of T lymphocyte activation, sirolimus affects the second phase, namely signal transduction and lymphocyte clonal proliferation.

  4. Skin conditions in dogs: Symptoms, causes, and how to help - AOL

    www.aol.com/skin-conditions-dogs-symptoms-causes...

    These specifically target the signals for itchiness and have the advantage of minimal side effects elsewhere in the body. "Immunotherapy can be utilized for atopic dogs.

  5. Sirolimus - Wikipedia

    en.wikipedia.org/wiki/Sirolimus

    Serious side effects including hypersensitivity and swelling have been observed in renal transplant patients. [22] While sirolimus was considered for treatment of LAM, it received orphan drug designation status because LAM is a rare condition. [22] The safety of LAM treatment by sirolimus in people younger than 18 years old has not been tested.

  6. Is Your Dog Stressed? 5 Signs to Watch for and How to Help - AOL

    www.aol.com/dog-stressed-5-signs-watch-151500398...

    CBD oil: If your dog is stressed because of pain (like arthritis), this has been proven to be helpful, but there is only anecdotal evidence that it will help dogs with stress. There are side ...

  7. Pimecrolimus - Wikipedia

    en.wikipedia.org/wiki/Pimecrolimus

    Pimecrolimus has a similar mode of action to that of tacrolimus but is more selective, with no effect on dendritic (Langerhans) cells. [19] It has lower permeation through the skin than topical steroids or topical tacrolimus [20] although they have not been compared with each other for their permeation ability through mucosa. In addition, in ...