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Dextromethorphan, or DXM, a common active ingredient found in many over-the-counter cough suppressant cold medicines, is used as a recreational drug and entheogen for its dissociative effects. [1] Street names include Brownies , Dextro , Drix , Gel , Groove , Lean , Mega-perls , Poor man's ecstasy , Poor man's PCP, Red devils , Robo , Rojo ...
Drug 1 Drug 2 Drug 3 Drug 4 Polysubstance slang, [2] [3] [4] or brand name Intoxication name Comment Any dissociative: Any dissociative: Void flip Void flipping Any dissociative: DMT: Dime bar, angel flip Dimension flipping, angel flipping Any depressant: Any stimulant: Speedball, powerball, over and under Powerballing, speedballing [5] Any ...
The effects of dissociatives can include sensory dissociation, hallucinations, mania, catalepsy, analgesia and amnesia. [ 4 ] [ 5 ] [ 6 ] According to Pender (1972), "the state has been designated as dissociative anesthesia since the patient truly seems disassociated from his environment."
NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.
Ketamine is used as a recreational drug for its hallucinogenic and dissociative effects. [24] When used recreationally, it is found both in crystalline powder and liquid form, and is often referred to by users as "Special K" or simply "K". The long-term effects of repeated use are largely unknown and are an area of active investigation.
Dextromethorphan is a prodrug of dextrorphan, which is the actual mediator of most of its dissociative effects through acting as a more potent NMDA receptor antagonist than dextromethorphan itself. [37] What role, if any, (+)-3-methoxymorphinan, dextromethorphan's other major metabolite, plays in its effects is not entirely clear. [38]
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Dextrorphan (DXO) is a psychoactive drug of the morphinan class which acts as an antitussive or cough suppressant and in high doses a dissociative hallucinogen. It is the dextrorotatory enantiomer of racemorphan; the levorotatory enantiomer is levorphanol. Dextrorphan is produced by O-demethylation of dextromethorphan by CYP2D6.