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PubMed is a free database including primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics. The United States National Library of Medicine (NLM) at the National Institutes of Health maintains the database as part of the Entrez system of information retrieval .
The main academic full-text databases are open archives or link-resolution services, although others operate under different models such as mirroring or hybrid publishers. . Such services typically provide access to full text and full-text search, but also metadata about items for which no full text is availa
PubMed Central is a free digital archive of full articles, accessible to anyone from anywhere via a web browser (with varying provisions for reuse). Conversely, although PubMed is a searchable database of biomedical citations and abstracts, the full-text article resides elsewhere (in print or online, free or behind a subscriber paywall).
The Entrez Global Query Cross-Database Search System is used at NCBI for all the major databases such as Nucleotide and Protein Sequences, Protein Structures, PubMed, Taxonomy, Complete Genomes, OMIM, and several others. [9] Entrez is both an indexing and retrieval system having data from various sources for biomedical research.
The National Library of Medicine runs the National Center for Biotechnology Information, which houses biological databases (PubMed among them) that are freely accessible on the Internet through the Entrez search engine [8] and Lister Hill National Center For Biomedical Communications. [9]
Entrez Global Query is an integrated search and retrieval system that provides access to all databases simultaneously with a single query string and user interface. Entrez can efficiently retrieve related sequences , structures , and references.
Cochrane researchers will perform searches of medical and health databases including MEDLINE/PubMed, EMBASE, PsycINFO, CINAHL, etc.; a continually updated database of trials called the Cochrane Central Register of Controlled Trials (CENTRAL); hand searching, where researchers look through entire libraries of scientific journals by hand and ...
Counterintuitively, a search that returns thousands of articles is not guaranteed to be comprehensive. Unlike using a typical Internet search engine, PubMed searching MEDLINE requires a little investment of time. Using the MeSH database to define the subject of interest is one of the most useful ways to improve the quality of a search.