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Gamma-aminobutyric acid, a GABA-B receptor agonist. A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. [1] There are three receptors of the gamma-aminobutyric acid. The ...
Recovery from benzodiazepine dependence tends to take a lot longer than recovery from alcohol, [47] [48] but people can regain their previous good health. [47] [medical citation needed] A review of the literature regarding benzodiazepine hypnotic drugs concluded that these drugs cause an unjustifiable risk to the individual and to public health.
Over time, insomnia can take a serious toll. That is especially the case for brain health , both Tiani and Sklar stress. While depression and anxiety can lead to insomnia, losing sleep can ...
Zaleplon is a high-selectivity, [26] high-affinity ligand of positive modulatory benzodiazepine sites on GABA A receptors. Zaleplon binds preferentially at benzodiazepine sites on α1-containing GABA A receptors (previously known as BZ1/Ω1 receptors), which largely mediate the sedative effects of benzodiazepines. [27]
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A GABA reuptake inhibitor (GRI) is a type of drug which acts as a reuptake inhibitor for the neurotransmitter gamma-Aminobutyric acid (GABA) by blocking the action of the gamma-Aminobutyric acid transporters (GATs). This in turn leads to increased extracellular concentrations of GABA and therefore an increase in GABAergic neurotransmission. [1]
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