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Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative. It is a first-generation H 1 -antihistamine and it works by blocking certain effects of histamine , which produces its antihistamine and sedative effects.
Benadryl Allergy is widely used as a sleep aid among adults. While it is not marketed as an over-the-counter (OTC) sleeping aid, most versions of Benadryl contain diphenhydramine, a drug with sedative properties. [6] Diphenhydramine (Benadryl) has also been used by parents to help improve their infant's sleep habits.
At some point before 1986, the Sominex formula had changed to diphenhydramine. [26] On January 17, 1989, the FDA approved the use of diphenhydramine hydrochloride and diphenhydramine citrate; [34] by then, Sominex and Sominex 2 both used at least one of these two chemical compounds. [33]
Phenyltoloxamine is widely used in preparations as an enhancing agent for some analgesics and antitussives (acetaminophen, dihydrocodeine, codeine, hydrocodone).It is widely used in certain parts of the world as cough suppressant usually with codeine, and sometimes by itself or in addition to dextromethorphan as it, like diphenhydramine, possesses antitussive action of its own and is ...
The first-generation sedating antihistamines diphenhydramine, doxepin, doxylamine, and pyrilamine are the most widely used medications in the world for preventing and treating insomnia. [6] As of 2004, doxylamine and diphenhydramine, which are both over-the-counter medications, were the agents most commonly used to treat short-term insomnia. [11]
Advil PM uses Diphenhydramine Citrate. Is this different from Diphenhydramine Hydrochloride, and should it be mentioned in Common Use? 76.86.119.54 07:09, 31 December 2007 (UTC) There is typically very little difference between a citrate and hydrochloride salt. In the case of Diphenhydramine the active part of the compound is an alkaloid (base).