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Neurulation refers to the folding process in vertebrate embryos, which includes the transformation of the neural plate into the neural tube. [1] The embryo at this stage is termed the neurula . The process begins when the notochord induces the formation of the central nervous system (CNS) by signaling the ectoderm germ layer above it to form ...
The neural fold is a structure that arises during neurulation in the embryonic development of both birds and mammals among other organisms. [1] [2] This structure is associated with primary neurulation, meaning that it forms by the coming together of tissue layers, rather than a clustering, and subsequent hollowing out, of individual cells (known as secondary neurulation).
Neurulation is a process in vertebrate embryos at the neurula stage in which the neural tube is formed. [6] [8] There are two types of neurulation: primary and secondary neurulation. Primary neurulation refers to the formation and inward folding of the neural plate upon itself to form the neural tube.
The formation and folding of the neural plate is the first step in primary neurulation. This is followed by the refinement and growth of neural plate cells. The third step of primary neurulation does not involve the neural plate per se, but rather the edges of the neural plate, which come together, turning the plate into the start of the neural ...
The neural plate folds outwards during the third week of gestation to form the neural groove. Beginning in the future neck region, the neural folds of this groove close to create the neural tube. The formation of the neural tube from the ectoderm is called neurulation.
The neural tube develops in two ways: primary neurulation and secondary neurulation. Primary neurulation divides the ectoderm into three cell types: The internally located neural tube; The externally located epidermis; The neural crest cells, which develop in the region between the neural tube and epidermis but then migrate to new locations
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During early embryonic development of the vertebrate, the dorsal ectoderm becomes specified to give rise to the epidermis and the nervous system; a part of the dorsal ectoderm becomes specified to neural ectoderm to form the neural plate which gives rise to the nervous system.