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Structural magnetic resonance imaging (structural MRI) of a head, from top to base of the skull. The first chapter of the history of neuroimaging traces back to the Italian neuroscientist Angelo Mosso who invented the 'human circulation balance', which could non-invasively measure the redistribution of blood during emotional and intellectual activity.
Functional near-infrared spectroscopy (fNIRS) is an optical brain monitoring technique which uses near-infrared spectroscopy for the purpose of functional neuroimaging. [1] Using fNIRS, brain activity is measured by using near-infrared light to estimate cortical hemodynamic activity which occur in response to neural activity.
Medical optical imaging is the use of light as an investigational imaging technique for medical applications, pioneered by American Physical Chemist Britton Chance. Examples include optical microscopy , spectroscopy , endoscopy , scanning laser ophthalmoscopy , laser Doppler imaging , optical coherence tomography , and transdermal optical imaging .
Optical imaging can measure the location and activity of specific regions of the brain by continuously monitoring blood hemoglobin levels through the determination of optical absorption coefficients. [19] [20] Infrascanner 1000, a NIRS scanner used to detect intracranial bleeding.
Event-related optical signal (EROS) is a neuroimaging technique that uses infrared light through optical fibers to measure changes in optical properties of active areas of the cerebral cortex. The fast optical signal (EROS) measures changes in infrared light scattering that occur with neural activity. [ 1 ]
Optical coherence tomography (OCT) is an imaging technique that uses interferometry with short-coherence-length light to obtain micrometer-level depth resolution and uses transverse scanning of the light beam to form two- and three-dimensional images from light reflected from within biological tissue or other scattering media.
The MR scanner acquires different slices within a single brain volume at different times, and hence the slices represent brain activity at different timepoints. Since this complicates later analysis, a timing correction is applied to bring all slices to the same timepoint reference.
99m Tc-exametazime SPECT scanning competes with fludeoxyglucose (FDG) PET scanning of the brain, which works to assess regional brain glucose metabolism, to provide very similar information about local brain damage from many processes. SPECT is more widely available, because the radioisotope used is longer-lasting and far less expensive in ...