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This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .
Myelosuppression, Stevens–Johnson syndrome (rare), pneumonitis (rare) and hepatitis (rare). Thiotepa: IV, topical Alkylates DNA. Breast, ovarian, and baldder cancer Myelosupression, embryo-fetal toxicity, hepatotoxicity (rare) [19] Trabectedin: IV Alkylates DNA. Advanced liposarcoma and leimyosarcoma
Stevens–Johnson syndrome (SJS) is a type of severe skin reaction. [1] Together with toxic epidermal necrolysis (TEN) and Stevens–Johnson/toxic epidermal necrolysis (SJS/TEN) overlap, they are considered febrile mucocutaneous drug reactions and probably part of the same spectrum of disease, with SJS being less severe.
Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a type of severe skin reaction. [2] Together with Stevens–Johnson syndrome (SJS) it forms a spectrum of disease, with TEN being more severe. [2] Early symptoms include fever and flu-like symptoms. [2] A few days later the skin begins to blister and peel forming painful raw ...
Stevens–Johnson syndrome, toxic epidermal necrolysis, and Stevens–Johnson syndrome/Toxic epidermal necrolysis overlap syndrome are a spectrum of Type IV, Subtype IVc, delayed hypersensitivity reactions, i.e. reactions initiated by CD8 + T cells and natural killer T cells. [2]
The most serious adverse effect is a hypersensitivity syndrome consisting of fever, skin rash, eosinophilia, hepatitis, and worsened renal function, collectively referred to as DRESS syndrome. [23] Allopurinol is one of the drugs commonly known to cause Stevens–Johnson syndrome and toxic epidermal necrolysis , two life-threatening ...
Allopurinol hypersensitivity syndrome (AHS) typically occurs in persons with preexisting kidney failure. [3]: 119 Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption [3]: 119 or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal ...
Bone marrow suppression, Stevens–Johnson syndrome. [3] [39] [40] Oxyphenisatin (Phenisatin) 1970s Australia, France, Germany, UK, US Hepatotoxicity. [3] Ozogamicin: 2010 US No improvement in clinical benefit; risk for death; veno-occlusive disease. [2] Pemoline (Cylert) 1997 Canada, UK Withdrawn from US in 2005 due to hepatotoxicity. [41] [3 ...