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Atrazine is a chlorinated herbicide of the triazine class. [2] It is used to prevent pre-emergence broadleaf weeds in crops such as maize (corn), [3] soybean [3] and sugarcane and on turf, such as golf courses and residential lawns.
In 1990 sulcotrione was introduced for post- emergence weed control in corn. Isoxaflutole opened the market more broadly for HPPD inhibitors when it was introduced in 1996 for corn and sugarcane, and for use as a pre-emergence herbicide that could control broadleaf weeds as did sulcotrione, but also additional grass weeds.
Atrazine is used on many U.S. crops, including corn and sugarcane. It has been banned in the European Union and several other countries and has been found to disrupt the endocrine system.
When 2,4-D was commercially released in 1946, it became the first successful selective herbicide, triggering a worldwide revolution in agricultural output. It allowed for greatly enhanced weed control in wheat, maize (corn), rice, and similar cereal grass crops, because it kills dicots (broadleaf plants), but not most monocots (grasses).
To prevent growth of crabgrass, preemergent herbicides must be applied at a critical time. If they are applied to the soil too early, they get washed too deep into the soil or washed away by rainwater. If they are applied too late, the key enzyme inhibited is no longer active. The best control requires a second application about 6–8 weeks later.
The U.S. EPA said in the 2003 Interim Reregistration Eligibility Decision, "The total or national economic impact resulting from the loss of atrazine to control grass and broadleaf weeds in corn, sorghum and sugarcane would be in excess of $2 billion per year if atrazine were unavailable to growers." In the same report, it added the "yield loss ...