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Geographic atrophy (GA), also known as atrophic age-related macular degeneration (AMD) or advanced dry AMD, is an advanced form of age-related macular degeneration that can result in the progressive and irreversible loss of retinal tissue (photoreceptors, retinal pigment epithelium, choriocapillaris) which can lead to a loss of central vision over time.
Induced pluripotent stem cell taken from blood cell and converted in retinal pigment epithelium. Stem cell therapy for macular degeneration is an emerging treatment approach aimed at restoring vision in individuals suffering from various forms of macular degeneration, particularly age-related macular degeneration (AMD). [1]
Treatment of AMD varies depending on the category of the disease at the time of diagnosis. In general, treatment is aimed at slowing down the progression of AMD. [69] As of 2018, there are no treatments to reverse the effects of AMD. [69] As of 2024, there are two drugs to dissolve the drusen in dry AMD, see below.
(Reuters) -Oyster Point Pharma Inc's treatment for dry eye disease became the first U.S. approved nasal spray for the chronic condition on Monday, sending the drug developer's shares about 19% ...
Ranibizumab, sold under the brand name Lucentis among others, is a monoclonal antibody fragment created from the same parent mouse antibody as bevacizumab.It is an anti-angiogenic [16] that is approved to treat the "wet" type of age-related macular degeneration (AMD, also ARMD), diabetic retinopathy, and macular edema due to branch retinal vein occlusion or central retinal vein occlusion.
Anecortave / æ n ə ˈ k ɔːr t eɪ v / is a novel angiogenesis inhibitor used in the treatment of the exudative (wet) form of age-related macular degeneration.Although similar in chemical structure to the corticosteroid hydrocortisone acetate, it possesses no glucocorticoid activity. [1]
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