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  2. Human genome - Wikipedia

    en.wikipedia.org/wiki/Human_genome

    The human genome was the first of all vertebrates to be sequenced to such near-completion, and as of 2018, the diploid genomes of over a million individual humans had been determined using next-generation sequencing. [61] These data are used worldwide in biomedical science, anthropology, forensics and other branches of science.

  3. N50, L50, and related statistics - Wikipedia

    en.wikipedia.org/wiki/N50,_L50,_and_related...

    The NG50 statistic is the same as N50 except that it is 50% of the known or estimated genome size that must be of the NG50 length or longer. This allows for meaningful comparisons between different assemblies. In the typical case that the assembly size is not more than the genome size, the NG50 statistic will not be more than the N50 statistic.

  4. Genome size - Wikipedia

    en.wikipedia.org/wiki/Genome_size

    Genome size ranges (in base pairs) of various life forms. Genome size is the total amount of DNA contained within one copy of a single complete genome.It is typically measured in terms of mass in picograms (trillionths (10 −12) of a gram, abbreviated pg) or less frequently in daltons, or as the total number of nucleotide base pairs, usually in megabases (millions of base pairs, abbreviated ...

  5. Cot analysis - Wikipedia

    en.wikipedia.org/wiki/Cot_analysis

    C 0 t analysis, a technique based on the principles of DNA reassociation kinetics, is a biochemical technique that measures how much repetitive DNA is in a DNA sample such as a genome. [1] It is used to study genome structure and organization and has also been used to simplify the sequencing of genomes that contain large amounts of repetitive ...

  6. ChIP-on-chip - Wikipedia

    en.wikipedia.org/wiki/ChIP-on-chip

    Array size: The first microarrays used for ChIP-on-Chip contained about 13,000 spotted DNA segments representing all ORFs and intergenic regions from the yeast genome. [2] Nowadays, Affymetrix offers whole-genome tiled yeast arrays with a resolution of 5bp (all in all 3.2 million probes).

  7. Centimorgan - Wikipedia

    en.wikipedia.org/wiki/Centimorgan

    Kong et al. calculated that the female genome is 4460 cM long, while the male genome is only 2590 cM long. [ 3 ] In contrast, in Plasmodium falciparum one centimorgan corresponds to about 15 kb ; markers separated by 15,000 nucleotides have an expected rate of chromosomal crossovers of 0.01 per generation.

  8. ENCODE - Wikipedia

    en.wikipedia.org/wiki/ENCODE

    The Encyclopedia of DNA Elements (ENCODE) is a public research project which aims "to build a comprehensive parts list of functional elements in the human genome." [2]ENCODE also supports further biomedical research by "generating community resources of genomics data, software, tools and methods for genomics data analysis, and products resulting from data analyses and interpretations."

  9. Personal genomics - Wikipedia

    en.wikipedia.org/wiki/Personal_genomics

    Personal genomics or consumer genetics is the branch of genomics concerned with the sequencing, analysis and interpretation of the genome of an individual. The genotyping stage employs different techniques, including single-nucleotide polymorphism (SNP) analysis chips (typically 0.02% of the genome), or partial or full genome sequencing.