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Dexamethasone is a fluorinated glucocorticoid medication [10] used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive pulmonary disease (COPD), croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), [11] and along with antibiotics in tuberculosis. [10]
Dexamethasone is an exogenous steroid that provides negative feedback to the pituitary gland to suppress the secretion of adrenocorticotropic hormone (ACTH). Specifically, dexamethasone binds to glucocorticoid receptors in the anterior pituitary gland, which lie outside the blood–brain barrier , resulting in regulatory modulation.
In pharmacologic (supraphysiologic) doses, glucocorticoids, such as prednisone, dexamethasone, and hydrocortisone are used to suppress various allergic, inflammatory, and autoimmune disorders. They are also administered as posttransplantory immunosuppressants to prevent the acute transplant rejection and graft-versus-host disease .
Dexamethasone – a synthetic glucocorticoid binds more powerfully to the glucocorticoid receptor than cortisol does. Dexamethasone is based on the cortisol structure but differs at three positions (extra double bond in the A-ring between carbons 1 and 2 and addition of a 9-α-fluoro group and a 16-α-methyl substituent).
Fabunan contains procaine hydrochloride, a water-soluble ester anesthetic, and dexamethasone sodium phosphate, a corticosteroid with well-known anti-inflammatory and immunosuppressant properties. [2] The solution is intended to be administered as an intramuscular injection.
Semaglutide Injection Instructions: Step-by-Step. Now that you know where to inject semaglutide, let’s walk through the steps with Craig Primack, MD, FACP, FAAP, MFOMA.Dr. Primack is a physician ...
Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF). It is useful in several applications, such as for spinal anesthesia, chemotherapy, or pain management. This route is also used to introduce drugs that fight ...
Ozempic. Like Rybelsus, Ozempic injections are FDA-approved for people with type 2 diabetes. This medication is meant to be used with healthy eating habits and exercise to improve blood sugar ...