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Anything that causes epilepsy causes epileptogenesis, because epileptogenesis is the process of developing epilepsy. Structural causes of epilepsy include neurodegenerative diseases , traumatic brain injury , stroke , brain tumor , infections of the central nervous system , and status epilepticus (a prolonged seizure or a series of seizures ...
Of those who have had a stroke, 6–10% develop epilepsy. [85] [86] Risk factors for post-stroke epilepsy include stroke severity, cortical involvement, hemorrhage and early seizures. [87] [88] Between 6 and 20% of epilepsy is believed to be due to head trauma. [72]
Animal models of epilepsy have helped to advance the understanding of how normal brains develop epilepsy (a process known as Epileptogenesis), and have been used in pre-clinical trials of antiepileptic drugs. [1] Epilepsy is a set of syndromes which have in common a predisposition to recurrent epileptic seizures. [2]
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A seizure is a sudden change in behavior, movement or consciousness due to abnormal electrical activity in the brain. [3] [6] Seizures can look different in different people.. It can be uncontrolled shaking of the whole body (tonic-clonic seizures) or a person spacing out for a few seconds (absence seizure
Kindling is a commonly used model for the development of seizures and epilepsy in which the duration and behavioral involvement of induced seizures increases after seizures are induced repeatedly. [1] Kindling is also referred as an animal visual model of epilepsy that can be produced by focal electrical stimulation in the brain.