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Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer. [18] It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in children and adults, but not recommended in elderly patients), rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura ...
Pregnant women with ITP are 1.83 times more likely to have bleeding episodes during pregnancy compared to non-pregnant females with ITP, however, with proper treatment, platelets rarely drop below 30,000. [63] In ITP, severe bleeding is a rare occurrence, and with treatment maternal deaths due to ITP are extremely rare. [63]
While the immune pathogenesis is ultimately demonstrated in many patients and early treatment is usually via immunosuppressants (e.g., prednisone, rituximab, etc.), immunosuppression is not a viable long-term treatment due to the cummulative (and sometimes fatal) side-effects of the pharmaceuticals involved, as well as the obvious problem of ...
This regimen can also be combined with the monoclonal antibody rituximab if the lymphoma is of B cell origin; this combination is called R-CHOP. In 2002, a randomized controlled trial showed a higher complete response rate for R-CHOP vs CHOP in elderly patients with Diffuse Large-B-Cell Lymphoma (76% vs 63%). [ 4 ]
MORE: US Marshals hunt for man suspected of killing 29-year-old woman, burying body in shallow grave “Due to his Santa-antics, Langlais was transported to a local hospital out of precaution and ...
UNITY TOWNSHIP, Pa. (KDKA) — The body of Elizabeth Pollard, the missing 64-year-old woman who fell through a sinkhole while looking for her cat in Unity Township, Pennsylvania, has been found ...
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