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Paroxysmal tonic upgaze (PTU) of childhood is a rare and distinctive neuro-ophthalmological syndrome characterized by episodes of sustained upward deviation of the eyes. Symptoms normally appear in babies under one year of age and are characterized by an upward stare or gaze, with the eyes rolled back, while the chin is typically held low.
An epicanthic fold or epicanthus [6] is a skin fold of the upper eyelid that covers the inner corner (medial canthus) of the eye. [3] However, variation occurs in the nature of this feature and the possession of "partial epicanthic folds" or "slight epicanthic folds" is noted in the relevant literature.
In the eyes, hypertelorism (widely set eyes) is a defining characteristic, present in 95% of people with Noonan syndrome. This may be accompanied by epicanthal folds (extra fold of skin at the inner corner of the eye), ptosis (drooping of the eyelids), proptosis (bulging eyes), strabismus (inward or outward turning of the eyes), nystagmus ...
The fissure may be increased in vertical height in Graves' disease, which is manifested as Dalrymple's sign.It is seen in disorders such as cri-du-chat syndrome. In animal studies using four times the therapeutic concentration of the ophthalmic solution latanoprost, the size of the palpebral fissure can be increased.
Widely spaced eyes, low hairline, drooping eyes, interdigital webbing, deformed ears, crossed eyes, and downward sloping palpebral fissures: TWIST1: Robinow–Sorauf syndrome: Widely spaced eyes, deviated septum, flat skull posterior, deformed ears, crossed eyes, protruding jaw, and duplication of distal phalanx: TWIST1: Muenke syndrome
Dauwerse–Peters syndrome, also known as Short stature, facial dysmorphism, severe brachydactyly and syndactyly, [1] is an extraordinarily rare novel genetic disorder which is characterized by a short height, depressed nasal bridge, flat facies, upward-slanting eyes, mild nostril anteversion, low-set ears, broad nasal root, severe generalized hand brachydactyly and 2nd-3rd toe syndactyly.
A fox eye lift is a cosmetic procedure that creates an almond-shaped eye look with a slight upward slant to the outer corner of the eye. It’s also known as a thread lift or canthoplasty.
Hypotropia is the similar condition, focus being on the eye with the visual axis lower than the fellow fixating eye. Dissociated vertical deviation is a special type of hypertropia leading to slow upward drift of one or rarely both eyes, usually when the patient is inattentive.