Ads
related to: x-ray crystallography and dna
Search results
Results From The WOW.Com Content Network
The method has also revealed the structure and function of many biological molecules, including vitamins, drugs, proteins and nucleic acids such as DNA. X-ray crystallography is still the primary method for characterizing the atomic structure of materials and in differentiating materials that appear similar in other experiments.
Photo 51 is an X-ray based fiber diffraction image of a paracrystalline gel composed of DNA fiber [1] taken by Raymond Gosling, [2] [3] a postgraduate student working under the supervision of Maurice Wilkins and Rosalind Franklin at King's College London, while working in Sir John Randall's group.
This is an accepted version of this page This is the latest accepted revision, reviewed on 22 December 2024. British X-ray crystallographer (1920–1958) This article is about the chemist. For the Mars rover named after her, see Rosalind Franklin (rover). Rosalind Franklin Franklin with a microscope in 1955 Born Rosalind Elsie Franklin (1920-07-25) 25 July 1920 Notting Hill, London, England ...
The importance of Bell's work on DNA is that, although today we know that several features of her proposed model are incorrect, it nevertheless showed that DNA had a regular, ordered structure that could be studied using X-ray crystallography and so laid the foundations for later work by Maurice Wilkins, Rosalind Franklin and Raymond Gosling ...
Rosalind Franklin joined King's College London in January 1951 to work on the crystallography of DNA. By the end of that year, she established two important facts: one is that phosphate groups, which are the molecular backbone for the nucleotide chains, lie on the outside (it was a general consensus at the time that they were at the inside); and the other is that DNA exists in two forms, a ...
X-ray crystallography is not common for nucleic acids alone, since neither DNA nor RNA readily form crystals. This is due to the greater degree of intrinsic disorder and dynamism in nucleic acid structures and the negatively charged (deoxy)ribose-phosphate backbones, which repel each other in close proximity.
X-ray crystallography is the primary method for determining the molecular conformations of biological macromolecules, particularly protein and nucleic acids such as DNA and RNA. The double-helical structure of DNA was deduced from crystallographic data.
X-ray scattering; Keto-enol tautomerism#DNA, the final key insight, from a Pauling collaborator, that the textbooks of the time were wrong, that led to the solved structure; Avery-MacLeod-McCarty experiment, the first demonstration that DNA was likely to be the genetic material; Chargaff's rules, which showed that A:T and G:C occurred in equal ...