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Perimenopausal Estrogen Replacement Therapy Study (PERT) [11] [12] [13] Postmenopausal Estrogen/Progestin Interventions (PEPI) Stockholm Trial or Stockholm Randomized Trial [14] [15] [10] Women's Estrogen for Stroke Trial (WEST) Women's Estrogen Lipid-Lowering Hormone Atherosclerosis Regression Trial (WELL-HART) Women's Health Initiative ...
Estrogen can also reduce vaginal atrophy and increase sexual arousal, frequency and orgasm. [22] The effectiveness of hormone replacement can decline in some women after long-term use. [22] A number of studies have also found that the combined effects of estrogen/androgen replacement therapy can increase libido and arousal over estrogen alone. [22]
Average number of moderate-to-severe hot flashes per week with placebo and different doses of oral estradiol in menopausal women [40] [41]. Estradiol is used in menopausal hormone therapy to prevent and treat moderate to severe menopausal symptoms such as hot flashes, vaginal dryness and atrophy, and osteoporosis (bone loss). [11]
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Other research has found that the rate of VTE is 1 to 5 in 10,000 woman-years in women who are not pregnant or taking a birth control pill, 3 to 9 in 10,000 woman-years in women who are on a birth control pill, 5 to 20 in 10,000 women-years in pregnant women, and 40 to 65 in 10,000 women-years in postpartum women. [104]
Board certified dermatologist Dr. Kristina Collins stresses the value of this massager for women going through menopause, where lower levels of estrogen can trigger more headaches.
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