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The alveoli are first located in the respiratory bronchioles as scattered outpockets, extending from their lumens. The respiratory bronchioles run for considerable lengths and become increasingly alveolated with side branches of alveolar ducts that become deeply lined with alveoli. The ducts number between two and eleven from each bronchiole. [10]
Alveoli are the spherical outcroppings of the respiratory bronchioles. Pulmonary surfactant is a surface-active complex of phospholipids and proteins formed by type II alveolar cells . [ 1 ] The proteins and lipids that make up the surfactant have both hydrophilic and hydrophobic regions.
The conducting zone also functions to offer a low resistance pathway for airflow. It provides a major defense role in its filtering abilities. The respiratory zone includes the respiratory bronchioles, alveolar ducts, and alveoli, and is the site of oxygen and carbon dioxide exchange with the blood. The respiratory bronchioles and the alveolar ...
Alveoli and their capillary networks 3D medical illustration showing different terminating ends of bronchioles. Alveoli consist of two types of alveolar cell and an alveolar macrophage. The two types of cell are known as type I and type II cells [32] (also known as pneumocytes). [3] Types I and II make up the walls and alveolar septa.
The air contained within the alveoli has a semi-permanent volume of about 2.5–3.0 liters which completely surrounds the alveolar capillary blood (Fig. 12). This ensures that equilibration of the partial pressures of the gases in the two compartments is very efficient and occurs very quickly.
Each respiratory bronchiole supplies the alveoli held in each acinus accompanied by a pulmonary artery branch. The pulmonary lobule is the portion of the lung ventilated by one bronchiole. Bronchioles are approximately 1 mm or less in diameter and their walls consist of ciliated cuboidal epithelium and a layer of smooth muscle .
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They also equalize the pressure in adjacent alveoli and, combined with increased distribution of surfactant, thus play an important role in prevention of collapse of the lung. [ 6 ] Unlike adults, in children these inter-alveolar connections are poorly developed which aids in limiting the spread of infection.