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Hydrophilic interaction chromatography (or hydrophilic interaction liquid chromatography, HILIC) [1] is a variant of normal phase liquid chromatography that partly overlaps with other chromatographic applications such as ion chromatography and reversed phase liquid chromatography. HILIC uses hydrophilic stationary phases with reversed-phase ...
[1] [2] As water is an excellent solvent and is also naturally abundant, it is a ubiquitous solvent in chemistry. Since water is frequently used as the solvent in experiments, the word solution refers to an aqueous solution, unless the solvent is specified. [3] [4] A non-aqueous solution is a solution in which the solvent is a liquid, but is ...
This Wikipedia page provides a comprehensive list of boiling and freezing points for various solvents.
Conversely, hydrophilic drugs (low octanol/water partition coefficients) are found primarily in aqueous regions such as blood serum. [4] If one of the solvents is a gas and the other a liquid, a gas/liquid partition coefficient can be determined.
A hydrophilicity plot is a quantitative analysis of the degree of hydrophobicity or hydrophilicity of amino acids of a protein.It is used to characterize or identify possible structure or domains of a protein.
Values for log K ow typically range between -3 (very hydrophilic) and +10 (extremely lipophilic/hydrophobic). [12] The values listed here [13] are sorted by the partition coefficient. Acetamide is hydrophilic, and 2,2′,4,4′,5-Pentachlorobiphenyl is lipophilic.
Ethyl acetate, a nail polish solvent. [1]A solvent (from the Latin solvÅ, "loosen, untie, solve") is a substance that dissolves a solute, resulting in a solution.A solvent is usually a liquid but can also be a solid, a gas, or a supercritical fluid.
The spreading property may be examined by adding a drop of the liquid onto an oily surface. If the liquid is not a wetting solution, the droplet will remain intact. If the liquid is a wetting solution, the droplet will spread uniformly on the oily surface because the formation of the micelles lowers the surface tension of the liquid. [6]