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Ketamine has been tested as a rapid-acting antidepressant [13] for treatment-resistant depression in bipolar disorder, and major depressive disorder. [14] Spravato, a nasal spray form of esketamine, was approved by the FDA in 2019 for use in treatment-resistant depression when combined with an oral antidepressant. [15] [16]
The risk factors [110] for treatment resistant depression are: the duration of the episode of depression, severity of the episode, if bipolar, lack of improvement in symptoms within the first couple of treatment weeks, anxious or avoidant and borderline comorbidity and old age. Treatment resistant depression is best handled with a combination ...
With treatment-resistant depression affecting about 30% of an estimated 21 million adults with major depressive disorder, the findings are “really promising,” Badran said.
Geriatric psychiatry is a subspecialty of psychiatry dealing with the research, diagnosis and treatment of mental disorders in the later stages of life. [1] [2] [3] The field composes of the diagnosis, treatment, and management of areas such as depression, dementia, and Alzheimer's disease. A geriatric psychiatrist is also a licensed doctor ...
In the immediate aftermath of a high-profile suicide of a beloved celebrity like Naomi Judd, calls to suicide-prevention hotlines tend to increase.
Major depression is more common in medically ill patients who are older than 70 years and hospitalized or institutionalized. Severe or chronic diseases associated with high rates of depression include stroke (30–60%), coronary heart disease (8–44%), cancer (1–40%), Parkinson's disease (40%), Alzheimer's disease (20–40%), and dementia ...
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