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Omeprazole, sold under the brand names Prilosec and Losec, among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome. [1] It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. [1]
A derivative of timoprazole, omeprazole, was discovered in 1979, and was the first of a new class of drug that control acid secretion in the stomach, a proton pump inhibitor (PPI). [11] [12] Addition of 5-methoxy-substitution to the benzimidazole moiety of omeprazole was also made and gave the compound much more stability at neutral pH. [6]
Proton-pump inhibitor. Proton-pump inhibitors (PPIs) are a class of medications that cause a profound and prolonged reduction of stomach acid production. They do so by irreversibly inhibiting the stomach's H + /K + ATPase proton pump. [1] Proton-pump inhibitors have largely superseded the H 2 -receptor antagonists, a group of medications with ...
Auxiliary labels stating "take with food or milk" and "do not take with aspirin". Auxiliary labels are small stickers consisting of one or more lines of text intended to enhance patient knowledge, with or without a pictogram. The directions for use included on the standard prescription label are typically limited to direct administration ...
Click through to see the shocking before and after images: The main side effects heroin causes on appearance according to New Health Advisor are: Weight loss due to loss of appetite, or because a ...
The drugmaker has settled a series of lawsuits related to Zantac over the past 12 months, including several in California. California is generally seen as a more challenging legal environment for ...
Esomeprazole's successful predecessor, omeprazole, is a mixture of two mirror-imaged molecules (esomeprazole which is the S-enantiomer, and R-omeprazole); critics said the company was trying to "evergreen" its omeprazole patent by patenting the pure esomeprazole and aggressively marketing to doctors that it is more effective than the mixture. [50]
The CPSC posted a warning Thursday that “Magnetic Chess Games” sold by China-based seller JOMO contain magnets that do not comply with U.S. federal safety regulations. The CPSC said it issued ...