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Trazodone's potent α 1-adrenergic blockade may cause some side effects like orthostatic hypotension and sedation. [114] Conversely, along with 5-HT 2A and H 1 receptor antagonism, it may contribute to its efficacy as a hypnotic. Trazodone lacks any affinity for the muscarinic acetylcholine receptors, so does not produce anticholinergic side ...
This is a list of adverse effects of the antidepressant trazodone, sorted by frequency of occurrence. Very common. Very common (>10% incidence) adverse effects ...
The TCAs are used primarily in the clinical treatment of mood disorders such as major depressive disorder (MDD), dysthymia, and treatment-resistant variants. They are also used in the treatment of a number of other medical disorders, including cyclic vomiting syndrome (CVS) and anxiety disorders such as generalized anxiety disorder (GAD), social phobia (SP) also known as social anxiety ...
Serotonin antagonist and reuptake inhibitors (SARIs) are a class of drugs used mainly as antidepressants, but also as anxiolytics and hypnotics. They act by antagonizing serotonin receptors such as 5-HT 2A and inhibiting the reuptake of serotonin, norepinephrine, and/or dopamine. Additionally, most also antagonize α 1 -adrenergic receptors.
Antidepressants may be modestly helpful for treating people who have both depression and alcohol dependence, however, the evidence supporting this association is of low quality. [ 68 ] Bupropion is used to help people stop smoking. Antidepressants are also used to control some symptoms of narcolepsy. [ 69 ]
Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [4][5][2] Symptoms in mild cases include high blood pressure and a fast heart rate; usually without a fever. [2]