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A lung nodule or pulmonary nodule is a relatively small focal density in the lung. ... Subsolid nodules [8] Total size <6 mm (<100mm 3) Total size >6mm (>100 3) Single
For lung nodules, air bronchograms used to be associated with infectious causes of consolidation and, therefore to be benign. However, in the setting of a lung nodule, an air bronchogram is actually more frequent in malignant than in benign nodules. [1] [4] studied the tumour-bronchus relationship and described five types: [1]
The presence of lung nodules on high resolution CT is a keystone in understanding the appropriate differential. Typically, the distribution of nodules is divided into perilymphatic, centrilobular and random categories. Furthermore, nodules can be ill-defined, implying they are in the alveoli, or well defined, suggesting an interstitial position ...
3. Nodule with poorly defined margins - Round density within the lung parenchyma, also called a tuberculoma. Nodules included in this category are those with margins that are indistinct or poorly defined (tree-in-bud sign [3]). The surrounding haziness can be either subtle or readily apparent and suggests coexisting airspace consolidation.
AAH is a pre-malignant cause of nodular GGO and is more commonly associated with lower attenuation on CT and smaller nodule size (<10 mm) compared to adenocarcinoma. [10] In addition, AAH often lacks the solid features and spiculated appearance that are often associated with malignant growths. [9]
The lesion itself serves as a biomarker, but the minute details of the lesion serve as biomarkers as well, and can collectively be used to assess the risk of neoplasm. Some of the imaging biomarkers used in lung nodule assessment include size, spiculation, calcification, cavitation, location within the lung, rate of growth, and rate of metabolism.
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