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Connective tissue disease, also known as connective tissue disorder, or collagen vascular diseases, refers to any disorder that affects the connective tissue. [1] The body's structures are held together by connective tissues, consisting of two distinct proteins : elastin and collagen .
Type II collagen is the basis for hyaline cartilage, including the articular cartilages at joint surfaces. It is formed by homotrimers of collagen, type II, alpha 1 chains. It makes up 50% of all protein in cartilage and 85–90% of collagen of articular cartilage.
Lupus is an autoimmune collagen vascular disorder that can be present with severe arthritis. In fact, about 90% of patients with Lupus have musculoskeletal involvement. [78] Symptoms in these patients can often mimic those of rheumatoid arthritis with similar stiffness and pain patterns.
There are two main benefits to improved nutrition: easing pain by adding foods that relieve arthritis and removing foods that make arthritis worse and reaching a healthy body mass index (BMI).
“Ill-fitting shoes and high heels may impair the way a person walks and offset the center of gravity, making arthritis pain worse,” says Dr. Dao. “Foot discomfort can translate vertically to ...
Collagen disease is a term previously used to describe systemic autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis), but now is thought to be more appropriate for diseases associated with defects in collagen, which is a component of the connective tissue.