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It can simply be an ethnic/genetic trait, [3] but was found in one study to occur in 25% of patients with atopic dermatitis. [4] The presence of Dennie–Morgan folds can be used as a diagnostic marker for allergy , [ 5 ] [ 6 ] with a sensitivity of 78% and specificity of 76% for atopic dermatitis according to one study, [ 7 ] although another ...
Atopic dermatitis (AD), also known as atopic eczema, is a long-term type of inflammation of the skin. [2] Atopic dermatitis is also often called simply eczema but the same term is also used to refer to dermatitis, the larger group of skin conditions. [2] [5] Atopic dermatitis results in itchy, red, swollen, and cracked skin. [2]
The Eczema Area and Severity Index (EASI) is a validated tool for the measurement of severity of atopic dermatitis. It ranges from 0 (no disease) to 72 (maximal disease). [1] [2] The EASI was developed in 1998 by modifying the Psoriasis Area and Severity Index (PASI), a widely accepted scoring system for psoriasis. [3]
The term atopic dermatitis was coined in 1933 by Wise and Sulzberger. [95] Sulfur as a topical treatment for eczema was fashionable in the Victorian and Edwardian eras. [84] The word dermatitis is from the Greek δέρμα derma 'skin' and -ῖτις-itis 'inflammation' and eczema is from Greek: ἔκζεμα ekzema 'eruption'. [96]
The SCORAD ("SCORing Atopic Dermatitis") index is a clinical tool for assessing the extent of the disease, disease intensity, and subjective symptoms of atopic dermatitis. [1] It gives approximate weights of 60% to intensity and 20% each to extent and subjective symptoms.
Immunosuppressants have seen use at low doses alongside systemic steroids and phototherapy for chronic symptoms of senile pruritus or dermatitis. Senile pruritus could have connections to the loss of tolerance for antigens on the skin that result from aging skin, which can potentially lead to other autoimmune disorders like bullous pemphigoid .
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