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The principle of hemodialysis is the same as other methods of dialysis; it involves diffusion of solutes across a semipermeable membrane. Hemodialysis utilizes counter current flow, where the dialysate is flowing in the opposite direction to blood flow in the extracorporeal circuit. Counter-current flow maintains the concentration gradient ...
Schematic of semipermeable membrane during hemodialysis, where blood is red, dialysing fluid is blue, and the membrane is yellow. Kidney dialysis (from Greek διάλυσις, dialysis, 'dissolution'; from διά, dia, 'through', and λύσις, lysis, 'loosening or splitting') is the process of removing excess water, solutes, and toxins from the blood in people whose kidneys can no longer ...
Renal replacement therapy includes dialysis (hemodialysis or peritoneal dialysis), hemofiltration, and hemodiafiltration, which are various ways of filtration of blood with or without machines. Renal replacement therapy also includes kidney transplantation, which is the ultimate form of replacement in that the old kidney is replaced by a donor ...
Dialysis occurs throughout nature and the principles of dialysis have been exploited by humans for thousands of years using natural animal or plant-based membranes. [2] [3] [4] The term dialysis was first routinely used for scientific or medical purposes in the late 1800s and early 1900s, pioneered by the work of Thomas Graham.
Dialysis is a common laboratory technique that operates on the same principle as medical dialysis. In the context of life science research, the most common application of dialysis is for the removal of unwanted small molecules such as salts, reducing agents, or dyes from larger macromolecules such as proteins , DNA , or polysaccharides . [ 2 ]
Kidney dialysis is the process of removing water, solutes and toxins from the blood of individuals with compromised kidney function, primary types of which are: Hemodialysis; Peritoneal dialysis; Hemofiltration; Liver dialysis, a detoxification treatment for liver failure. Dialysis, a genus of insects in the family Xylophagidae
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Hemofiltration is sometimes used in combination with hemodialysis, when it is termed hemodiafiltration. Blood is pumped through the blood compartment of a high flux dialyzer, and a high rate of ultrafiltration is used, so there is a high rate of movement of water and solutes from blood to dialysate that must be replaced by substitution fluid that is infused directly into the blood line.