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Side effects are more common in people with liver problems. [6] Use during pregnancy may harm the baby. [6] Docetaxel is in the taxane family of medications. [9] It works by disrupting the normal function of microtubules and thereby stopping cell division. [6] Docetaxel was patented in 1986 and approved for medical use in 1995. [10]
Docetaxel has the minimal structure modifications at C13 side chain and C10 substitution showed more water solubility and more potency than paclitaxel. Clinical trials have shown that patients who develop hypersensitivity to paclitaxel may receive docetaxel without an allergic response.
Nausea and vomiting are two of the most feared cancer treatment-related side-effects for people with cancer and their families. In 1983, Coates et al. found that people receiving chemotherapy ranked nausea and vomiting as the first and second most severe side-effects, respectively. [98]
Cialis has several common side effects, many of which also happen with other drugs used to treat ED, like sildenafil (generic Viagra®), vardenafil , and avanafil (Stendra®).
The average monthly retail price of Ozempic ranges from $1,000 or more without insurance, per GoodRx. People may also pursue microdosing to reduce the incidence or severity of side effects such as ...
Constipation and an upset stomach are among the most common side effects associated with oral iron supplements, Cunningham says.
The systems of the body most affected by chemotherapy drugs include visual and semantic memory, attention and motor coordination and executive functioning. [9] [10] These effects can impair a chemotherapy patient's ability to understand and make decisions regarding treatment, perform in school or employment and can reduce quality of life. [10]
Cabazitaxel and docetaxel demonstrated different toxicity profiles, and C20 showed the overall lowest toxicity. [12] In a phase III trial with 755 men for the treatment of castration-resistant prostate cancer , median survival was 15.1 months for participants receiving cabazitaxel versus 12.7 months for participants receiving mitoxantrone .
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