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  2. Fuchs' dystrophy - Wikipedia

    en.wikipedia.org/wiki/Fuchs'_dystrophy

    Fuchs dystrophy, also referred to as Fuchs endothelial corneal dystrophy (FECD) and Fuchs endothelial dystrophy (FED), is a slowly progressing corneal dystrophy that usually affects both eyes and is slightly more common in women than in men. Although early signs of Fuchs dystrophy are sometimes seen in people in their 30s and 40s, the disease ...

  3. Corneal dystrophy - Wikipedia

    en.wikipedia.org/wiki/Corneal_dystrophy

    Recurrent corneal erosions may occur. The hallmark of Schnyder corneal dystrophy is the accumulation of crystals within the corneal stroma which cause corneal clouding typically in a ring-shaped fashion. [citation needed] Posterior corneal dystrophies – Fuchs corneal dystrophy presents during the fifth or sixth decade of life. The ...

  4. Posterior polymorphous corneal dystrophy - Wikipedia

    en.wikipedia.org/wiki/Posterior_polymorphous...

    Posterior polymorphous corneal dystrophy (PPCD; sometimes also Schlichting dystrophy) is a type of corneal dystrophy, characterised by changes in Descemet's membrane and endothelial layer. Symptoms mainly consist of decreased vision due to corneal edema. In some cases they are present from birth, other patients are asymptomatic.

  5. Descemet's membrane - Wikipedia

    en.wikipedia.org/wiki/Descemet's_membrane

    Copper disposition on corneal Descemet's membrane. Significant damage to the membrane may require a corneal transplant. Damage caused by the hereditary condition known as Fuchs dystrophy (q.v.)—where Descemet's membrane progressively fails and the cornea thickens and clouds because the exchange of nutrients/fluids between the cornea and the rest of the eye is interrupted—can be reversed by ...

  6. Bullous keratopathy - Wikipedia

    en.wikipedia.org/wiki/Bullous_keratopathy

    Bullous keratopathy, also known as pseudophakic bullous keratopathy (PBK), is a pathological condition in which small vesicles, or bullae, are formed in the cornea due to endothelial dysfunction. In a healthy cornea, endothelial cells keeps the tissue from excess fluid absorption, pumping it back into the aqueous humor.

  7. Congenital hereditary endothelial dystrophy - Wikipedia

    en.wikipedia.org/wiki/Congenital_hereditary...

    Congenital hereditary corneal dystrophy (CHED) is a form of corneal endothelial dystrophy that presents at birth. CHED was previously subclassified into two subtypes: CHED1 and CHED2. However in 2015, the International Classification of Corneal Dystrophies (IC3D) renamed the condition "CHED1" to become posterior polymorphous corneal dystrophy ...

  8. Collagen, type VIII, alpha 2 - Wikipedia

    en.wikipedia.org/wiki/Collagen,_type_VIII,_alpha_2

    329941 Ensembl ENSG00000171812 ENSMUSG00000056174 UniProt P25067 Q4VAQ0 P25318 RefSeq (mRNA) NM_001294347 NM_005202 NM_199473 RefSeq (protein) NP_001281276 NP_005193 NP_955767 Location (UCSC) Chr 1: 36.1 – 36.13 Mb Chr 4: 126.18 – 126.21 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Collagen alpha-2(VIII) chain is a protein that in humans is encoded by the COL8A2 gene ...

  9. Corneal endothelium - Wikipedia

    en.wikipedia.org/wiki/Corneal_endothelium

    Leading causes of endothelial failure include inadvertent endothelial trauma from intraocular surgery (such as cataract surgery) and Fuchs' dystrophy. Surgical causes of endothelial failure include both acute intraoperative trauma as well as chronic postoperative trauma, such as from a malpositioned intraocular lens or retained nuclear fragment ...