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Mycosis fungoides, also known as Alibert-Bazin syndrome or granuloma fungoides, [1] is the most common form of cutaneous T-cell lymphoma. It generally affects the skin, but may progress internally over time.
The presentation depends if it is mycosis fungoides or Sézary syndrome, the most common, though not the only types. Among the symptoms for the aforementioned types are: enlarged lymph nodes, an enlarged liver and spleen, and non-specific dermatitis. [1]
Fungal infection, also known as mycosis, is a disease caused by fungi. [ 5 ] [ 13 ] Different types are traditionally divided according to the part of the body affected; superficial, subcutaneous , and systemic.
The premycotic phase is a phase of mycosis fungoides in which a patient has areas of red, scaly, itchy skin on areas of the body that are usually not exposed to sun. This is early-phase mycosis fungoides, but it is hard to diagnose the rash as mycosis fungoides during this phase. The premycotic phase may last from months to decades.
The effects of Mycosis Fungoides on the skin during the plaque or tumor phase. Signs and Symptoms: 4 Phases: [12] Premycotic Phase: Scale-like red rash on areas of the skin that are not exposed to the sun. Patch Phase: An itchy, thin rash; Plaque Phase: Raised bumps or lesions present on the skin
Pagetoid reticulosis is a very slow progressive variant of mycosis fungoides and is usually localized unlike the latter. [4] Treatment
Sézary disease and mycosis fungoides are cutaneous T-cell lymphomas having a primary manifestation in the skin. [5] The disease's origin is a peripheral CD4+ T-lymphocyte, [3] although rarer CD8+/CD4- cases have been observed. [3]
One of the symptoms of Mycosis fungoide include Differences in T-cell lymphoma subtypes extend to the clinical characteristics and symptoms of the disease with each varying drastically. As a result, there is almost no universally known symptom that can be applied to all T-cell lymphoma subtypes.