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  2. Cardiac action potential - Wikipedia

    en.wikipedia.org/wiki/Cardiac_action_potential

    (A brief chemical gradient driven efflux of Na+ through the connexon at peak depolarization causes the conduction of cell to cell depolarization, not potassium.) [27] These connections allow for the rapid conduction of the action potential throughout the heart and are responsible for allowing all of the cells in the atria to contract together ...

  3. Depolarization - Wikipedia

    en.wikipedia.org/wiki/Depolarization

    Depolarization is essential to the function of many cells, communication between cells, and the overall physiology of an organism. Action potential in a neuron, showing depolarization, in which the cell's internal charge becomes less negative (more positive), and repolarization, where the internal charge returns to a more negative value.

  4. Ventricular action potential - Wikipedia

    en.wikipedia.org/wiki/Ventricular_action_potential

    The plateau lasts on the order of 100 ms. At the time that calcium channels are getting activated, channels that mediate the transient outward potassium current open as well. This outward potassium current causes a small dip in membrane potential shortly after depolarization. This current is observed in human and dog action potentials, but not ...

  5. Afterdepolarization - Wikipedia

    en.wikipedia.org/wiki/Afterdepolarization

    Delayed afterdepolarizations (DADs) begin during phase 4, after repolarization is completed but before another action potential would normally occur via the normal conduction systems of the heart. They are due to elevated cytosolic calcium concentrations, classically seen with digoxin toxicity.

  6. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    The pattern of prepotential or spontaneous depolarization, followed by rapid depolarization and repolarization just described, are seen in the SA node and a few other conductive cells in the heart. Since the SA node is the pacemaker, it reaches threshold faster than any other component of the conduction system.

  7. T wave - Wikipedia

    en.wikipedia.org/wiki/T_wave

    Repolarization of the ventricle happens in the opposite direction of depolarization and is negative current, signifying the relaxation of the cardiac muscle of the ventricles. But this negative flow causes a positive T wave; although the cell becomes more negatively charged, the net effect is in the positive direction, and the ECG reports this ...

  8. Pacemaker potential - Wikipedia

    en.wikipedia.org/wiki/Pacemaker_potential

    Because the pacemaker potential represents the non-contracting time between heart beats , it is also called the diastolic depolarization. The amount of net inward current required to move the cell membrane potential during the pacemaker phase is extremely small, in the order of few pAs, but this net flux arises from time to time changing ...

  9. Cardiac pacemaker - Wikipedia

    en.wikipedia.org/wiki/Cardiac_pacemaker

    Though much faster than the depolarization of phase 4, the upstroke in a pacemaker cell is slow compared to that in an axon. The SA and AV node do not have fast sodium channels like neurons, and the depolarization is mainly caused by a slow influx of calcium ions. (The funny current also increases).