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Warthin's tumor, also known as papillary cystadenoma lymphomatosum, is a benign cystic tumor of the salivary glands containing abundant lymphocytes and germinal centers (lymph node-like stroma). It is named for pathologist Aldred Scott Warthin , who described two cases in 1929.
Salivary gland tumours, or neoplasms, are tumours that form in the tissues of salivary glands.The salivary glands are classified as major or minor.The major salivary glands consist of the parotid, submandibular, and sublingual glands.
Cytopathology of Warthin's tumor, with typical cellular features (and a relatively uncommon binucleated cell). [1] Pap stain. The relatively large size of the oncocytes is seen when comparing to the lymphocyte. Micrograph showing apocrine-type metaplasia of the breast with typical oncocytes. [2] H&E stain.
–conducted to help the surgeon locate the tumor and address complications (i.e. the extent of the neoplasm and its resulting excision). Fine-needle aspiration - technique in helping the surgeon to physically diagnose the malignancy of the tumor; Neck dissection - only considered in the most extreme of cases before a parotidectomy.
Aldred Scott Warthin (October 21, 1866 − May 23, 1931) was an American pathologist whose research laid the foundation for understanding the heritability of certain cancers. He has been described as "the father of cancer genetics ."
At surgery, it was found to be a soft 3.0 × 2.1 × 1.8 cm tumor of the submandibular salivary gland. The photo shows the characteristic dark color of an oncocytoma, a rare type of benign neoplasm, at the left side of the image (the normal lobulated salivary gland tissue is to the right).
The growth of the tumor can spread to nearby areas such as the ischiorectal fossa and inguinal lymph nodes. Approximately 50% of bartholin gland carcinomas originate from squamous cell carcinomas . Another uncommon characteristic of Bartholin gland malignancies is that the growth of a lesion originates from the three types of epithelial tissue ...
Adenoid cystic carcinoma is a rare type of cancer that can exist in many different body sites. This tumor most often occurs in the salivary glands, but it can also be found in many anatomic sites, including the breast, [1] [2] lacrimal gland, lung, brain, Bartholin gland, trachea, and the paranasal sinuses.