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  2. Huntington's disease - Wikipedia

    en.wikipedia.org/wiki/Huntington's_disease

    Predictive testing for Huntington's disease has been available via linkage analysis (which requires testing multiple family members) since 1986 and via direct mutation analysis since 1993. [68] At that time, surveys indicated that 50–70% of at-risk individuals would have been interested in receiving testing, but since predictive testing has ...

  3. Do You Really Want to Know? - Wikipedia

    en.wikipedia.org/wiki/Do_You_Really_Want_to_Know?

    The main subjects of the film are Jeff Carroll, a US Army Veteran and Huntington's disease researcher from Washington; Dr. John Roder, a renowned cancer specialist at the Samuel Lunenfeld Research Institute at Mount Sinai Hospital, Toronto; Theresa Monahan of Ohio, who was among the first Americans to undergo predictive testing for Huntington's disease in 1988, and Dr. Michael R. Hayden, who ...

  4. Lead time bias - Wikipedia

    en.wikipedia.org/wiki/Lead_time_bias

    No additional life span has been gained, and the patient may even be subject to added anxiety as the patient must live for longer with knowledge of the disease. For example, the genetic disorder Huntington's disease is diagnosed when symptoms appear at around 50, and the person dies at around 65. The typical patient, therefore, lives about 15 ...

  5. The Lion's Mouth Opens - Wikipedia

    en.wikipedia.org/wiki/The_Lion's_Mouth_Opens

    The film begins at a dinner party. Filmmaker and actress Marianna Palka, 33 years old, is joined by friends in anticipation of the genetic testing results she will receive the next day, revealing whether or not she has inherited the presently untreatable neurodegenerative illness, Huntington's disease, from her father, who has the illness.

  6. Anticipation (genetics) - Wikipedia

    en.wikipedia.org/wiki/Anticipation_(genetics)

    Once the number of copies reaches over 100, the disease will manifest earlier in life (although the individual will still reach adulthood before the symptoms are evident) and the symptoms will be more severe – including electrical myotonia. As the number progresses upwards past 400, the symptoms show themselves during childhood or infancy.

  7. Huntington's Disease Outreach Project for Education at Stanford

    en.wikipedia.org/wiki/Huntington's_Disease...

    The Huntington's disease Outreach Project for Education at Stanford (HOPES) is a student-run project at Stanford University dedicated to making scientific information about Huntington's disease (HD) more readily accessible to patients and the public.

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