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If the Benchmark score is determined by the transformation products, the Benchmark score will include a subscript of TP. CoHC - Chemicals of High Concern (polymer residuals & catalysts): Version 1.4 of the GreenScreen added special rules for benchmarking polymers which include analysis of residual monomers and/or catalysts present at or above ...
These infections can include Helicobacter pylori due to this species not favouring an acid environment, leading to an increased risk of ulcers and gastric cancer risk in genetically susceptible patients. [50] PPI use in people who have received attempted H. pylori eradication may also be associated with an increased risk of gastric cancer. [51]
The United States Environmental Protection Agency defines NOAEL as 'an exposure level at which there are no statistically or biologically significant increases in the frequency or severity of adverse effects between the exposed population and its appropriate control; some effects may be produced at this level, but they are not considered as adverse, or as precursors to adverse effects. [5]
Cancer slope factors (CSF) are used to estimate the risk of cancer associated with exposure to a carcinogenic or potentially carcinogenic substance. A slope factor is an upper bound, approximating a 95% confidence limit , on the increased cancer risk from a lifetime exposure to an agent by ingestion or inhalation .
This is the WikiProject Chemistry/Assessment page. For further details on chemical compounds, see: Wikipedia:WikiProject Chemicals/Assessment Article assessments are tracked through the following pages:
Chemical Safety Reports are the main end point for data assessment under REACH (the European Community Regulation on chemicals and their safe use, concerning the Registration, Evaluation, Authorisation and Restriction of Chemical substances [4]) in which hazard and exposure data are considered together to assess the risk of a substance. [5]
The journal covers developments in "medicinal chemistry and rational drug design for the discovery of anti-cancer agents" and publishes original research reports and review papers. [ 1 ] It is related to the journal Current Medicinal Chemistry and was established in 2001 as Current Medicinal Chemistry – Anti-Cancer Agents . [ 2 ]
Diagram depicting a representative pan-assay interference compound. The drug-like molecule specifically interacts with target B, but the PAINS-like compound non-specifically interacts with multiple targets