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  2. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    Grapefruit–drug interactions that affect the pre-systemic metabolism (i.e., the metabolism that occurs before the drug enters the blood) of drugs have a different duration of action than interactions that work by other mechanisms, such as on absorption, discussed below.

  3. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/lifestyle/grapefruit-interfere...

    That's why it's important to find out from your health care provider or a pharmacist if any of your medications interact with grapefruit. In addition, grapefruit can have the opposite effect on ...

  4. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs. Interactions may occur by simultaneous targeting of receptors , directly or indirectly. For example, both Zolpidem and alcohol affect GABA A receptors , and their simultaneous consumption results in the overstimulation of the receptor, which can ...

  5. Grapefruit juice - Wikipedia

    en.wikipedia.org/wiki/Grapefruit_juice

    Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]

  6. Can grapefruit boost your immune system and help you lose ...

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    “A whole grapefruit provides nearly 100% of the recommended daily value of vitamin C, a powerful antioxidant, which can boost the immune system,” Politi tells TODAY.com.

  7. Aliskiren - Wikipedia

    en.wikipedia.org/wiki/Aliskiren

    Aliskiren (brand names Tekturna and Rasilez) is the first in a class of drugs called direct renin inhibitors. It is used for essential (primary) hypertension . [ 2 ] While used for high blood pressure, other better studied medications are typically recommended due to concerns of higher side effects and less evidence of benefit.

  8. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/grapefruit-interfere-medications...

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  9. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...