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2. High-grade prostatic intraepithelial neoplasia - Wikipedia

   en.wikipedia.org/wiki/High-grade_prostatic...

   There are several reasons why PIN is the most likely prostate cancer precursor. [3] PIN is more common in men with prostate cancer. High grade PIN can be found in 85 to 100% of radical prostatectomy specimens, [4] nearby or even in connection with prostate cancer. It tends to occur in the peripheral zone of the prostate.

3. Prostate biopsy - Wikipedia

   en.wikipedia.org/wiki/Prostate_biopsy

   Prostate biopsy is a procedure in which small hollow needle-core samples are removed from a man's prostate gland to be examined for the presence of prostate cancer. It is typically performed when the result from a PSA blood test is high. [1] It may also be considered advisable after a digital rectal exam (DRE) finds possible abnormality.

4. Prostate enlargement, how it affects men as they age, and its ...

   www.aol.com/prostate-enlargement-affects-men-age...

   So an elevated PSA does not mean the patient has prostate cancer. In fact, only about 25% of patients with elevated PSAs are found to have prostate cancer on biopsy when 4 mg/dl is used as the cut ...

5. Prostatic acid phosphatase - Wikipedia

   en.wikipedia.org/wiki/Prostatic_acid_phosphatase

   PAP immunohistochemical staining is often used with PSA (staining), by pathologists, to help distinguish poorly differentiated carcinomas.For example, poorly differentiated prostate adenocarcinoma (prostate cancer) and urothelial carcinoma (bladder cancer) may appear similar under the microscope, but PAP and PSA staining can help differentiate them; [7] prostate adenocarcinoma often stains ...

6. Gleason grading system - Wikipedia

   en.wikipedia.org/wiki/Gleason_grading_system

   The Gleason grading system is used to help evaluate the prognosis of men with prostate cancer using samples from a prostate biopsy. Together with other parameters, it is incorporated into a strategy of prostate cancer staging which predicts prognosis and helps guide therapy. A Gleason score is given to prostate cancer based upon its microscopic ...

7. Prostate cancer - Wikipedia

   en.wikipedia.org/wiki/Prostate_cancer

   Those with high levels of PSA in their blood are at increased risk for developing prostate cancer. Diagnosis requires a biopsy of the prostate. If cancer is present, the pathologist assigns a Gleason score; a higher score represents a more dangerous tumor. Medical imaging is performed to look for cancer that has spread outside the prostate.