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Multiple system atrophy is estimated to affect approximately 5 per 100,000 people. At autopsy, many patients diagnosed during life with Parkinson's disease are found actually to have MSA, suggesting that the actual incidence of MSA is higher than that estimate. [ 4 ]
Attention deficit hyperactivity disorder management options are evidence-based practices with established treatment efficacy for ADHD.Approaches that have been evaluated in the management of ADHD symptoms include FDA-approved pharmacologic treatment and other pharmaceutical agents, psychological or behavioral approaches, combined pharmacological and behavioral approaches, cognitive training ...
There are three main types of synucleinopathy: Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). [1] Other rare disorders, such as various neuroaxonal dystrophies, also have α-synuclein pathologies. [2]
Additional Parkinson-plus syndromes include Pick's disease and olivopontocerebellar atrophy. [7] The latter is characterized by ataxia and dysarthria, and may occur either as an inherited disorder or as a variant of multiple system atrophy. MSA is also characterized by autonomic failure, formerly known as Shy–Drager syndrome. [8]
Pure autonomic failure originates from peripheral autonomic nervous system lesions. [ 6 ] The diagnosis of pure autonomic failure relies on the absence of other neurologic abnormalities, specifically Parkinsonism , cognitive impairment, cerebellar ataxia , or tremors, and on compatible clinical features of subtle, progressive pan autonomic ...
Males with ADHD, children, and adults exhibit higher rates of externalizing disorders or behaviors that manifest as aggressive, disruptive, rule-breaking behaviors, making them more likely to be referred for ADHD treatment. Adult males with ADHD are also more likely to display antisocial behaviors associated with antisocial personality disorder ...