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  2. Daratumumab - Wikipedia

    en.wikipedia.org/wiki/Daratumumab

    Daratumumab binds to a different CD38 epitope amino-acid sequence than does the anti-CD38 monoclonal antibody isatuximab. [21] Daratumumab binds to CD38, causing cells to apoptose via antibody-dependent cellular cytotoxicity , complement-dependent cytotoxicity , inhibition of mitochondrial transfer or antibody-dependent cellular phagocytosis .

  3. Daratumumab/hyaluronidase - Wikipedia

    en.wikipedia.org/wiki/Daratumumab/hyaluronidase

    It was approved for use in the United States in May 2020. [2] [7] [8]Efficacy of daratumumab and hyaluronidase-fihji (monotherapy) was evaluated in the COLUMBA trial (NCT03277105), an open-label non-inferiority trial randomizing 263 participants to daratumumab and hyaluronidase-fihj and 259 to intravenous daratumumab (daratumumab IV). [2]

  4. Isatuximab - Wikipedia

    en.wikipedia.org/wiki/Isatuximab

    Isatuximab, sold under the brand name Sarclisa, is a monoclonal antibody (mAb) medication for the treatment of multiple myeloma. [6] [4]The most common side effects include neutropenia (low levels of neutrophils, a type of white blood cell), infusion reactions, pneumonia (infection of the lungs), upper respiratory tract infection (such as nose and throat infections), diarrhoea and bronchitis ...

  5. CD38 - Wikipedia

    en.wikipedia.org/wiki/CD38

    952 12494 Ensembl ENSG00000004468 ENSMUSG00000029084 UniProt P28907 P56528 RefSeq (mRNA) NM_001775 NM_007646 RefSeq (protein) NP_001766 NP_031672 Location (UCSC) Chr 4: 15.78 – 15.85 Mb Chr 5: 44.03 – 44.07 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase, is a glycoprotein found on the surface of many ...

  6. Weight Loss Injections: What You Need to Know, From ... - AOL

    www.aol.com/lifestyle/weight-loss-injections...

    Weight loss injections are safe and effective when used as prescribed. GLP-1s are usually prescribed alongside a healthy diet and frequent exercise. GLP-1s are usually prescribed alongside a ...

  7. Immunoglobulin therapy - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_therapy

    Immunoglobulin therapy is the use of a mixture of antibodies (normal human immunoglobulin) to treat several health conditions. [13] [14] These conditions include primary immunodeficiency, immune thrombocytopenic purpura, chronic inflammatory demyelinating polyneuropathy, Kawasaki disease, certain cases of HIV/AIDS and measles, Guillain–Barré syndrome, and certain other infections when a ...

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