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The indium white blood cell scan is a nuclear medicine procedure in which white blood cells (mostly neutrophils) are removed from the patient, tagged with the radioisotope Indium-111, and then injected intravenously into the patient. The tagged leukocytes subsequently localize to areas of relatively new infection.
Indium-111 (111 In) is a radioactive isotope of indium (In). It decays by electron capture to stable cadmium-111 with a half-life of 2.8 days. [3] Indium-111 chloride (111 InCl) solution is produced by proton irradiation of a cadmium target (112 Cd(p,2n) or 111 Cd(p,n)) in a cyclotron, as recommended by International Atomic Energy Agency (IAEA). [4]
An excess of white blood cells is usually due to infection or inflammation. Less commonly, a high white blood cell count could indicate certain blood cancers or bone marrow disorders. The number of leukocytes in the blood is often an indicator of disease, and thus the white blood cell count is an important subset of the complete blood count.
Indium-115 makes up 95.7% of all indium. Indium is one of three known elements (the others being tellurium and rhenium) of which the stable isotope is less abundant in nature than the long-lived primordial radioisotopes. [37] The stablest artificial isotope is indium-111, with a half-life of approximately 2.8 days. All other isotopes have half ...
A scanning electron microscope image of normal circulating human blood. One can see red blood cells, several knobby white blood cells including lymphocytes, a monocyte, a neutrophil, and many small disc-shape platelets. White blood cells (WBCs) are also known as leukocytes. Most leukocytes differ from other cells of the body in that they are ...
This is a list of immune cells, also known as white blood cells, white cells, leukocytes, or leucocytes. They are cells involved in protecting the body against both infectious disease and foreign invaders .
Indium-111 is also used in indium white blood cell scans, which use nuclear medical techniques to search for hidden infections. Several proton-rich isotopes of indium (including indium-99) have been used to measure the mass of the doubly-magic isotope tin-100. [5] [6]
The condition of having too few white blood cells is leukopenia, while having too many is leukocytosis. There are individual terms for the lack or overabundance of specific types of white blood cells. The number of white blood cells in circulation is commonly increased in the incidence of infection. [5]