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Mycobacterium leprae (also known as the leprosy bacillus or Hansen's bacillus) is one [a] of the two species of bacteria that cause Hansen's disease (leprosy), [1] a chronic but curable infectious disease that damages the peripheral nerves and targets the skin, eyes, nose, and muscles.
Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria Mycobacterium leprae or Mycobacterium lepromatosis. [ 4 ] [ 7 ] Infection can lead to damage of the nerves , respiratory tract , skin, and eyes. [ 4 ]
Mycobacterium is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis ( M. tuberculosis ) and leprosy ( M. leprae ) in humans.
Mycobacterium lepraemurium Scientific classification Domain: Bacteria Phylum: Actinomycetota Class: Actinomycetia Order: Mycobacteriales Family: Mycobacteriaceae Genus: Mycobacterium Species: M. lepraemurium Binomial name Mycobacterium lepraemurium Marchoux and Sorel 1912 Mycobacterium lepraemurium is a causative agent of feline leprosy. It causes granulomatous lesions, characteristic of the ...
The history of leprosy was traced to its origins by an international team of 22 geneticists using comparative genomics of the worldwide distribution of Mycobacterium leprae. [1] Monot et al. (2005) determined that leprosy originated in East Africa or the Near East and traveled with humans along their migration routes, including those of trade ...
Mycobacterium lepromatosis can induce diffuse lepromatous leprosy (DLL), typically known to occur in Mexico and the Caribbean. [5] [6] DLL is a severe form of leprosy which manifests through nerve invasion and extensive skin ulcerations due to massive AFB burden in internal organs. [5]
Leprosy, sometimes known as Hansen's disease, is an infectious disease caused by Mycobacterium leprae, an aerobic, acid-fast, rod-shaped mycobacterium. The modern term for the disease is named after the discoverer of the bacterium, Gerhard Armauer Hansen .
Hansen remained medical officer for leprosy in Norway and it was through his efforts that the leprosy acts of 1877 and 1885 were passed, leading to a steady decline of the disease in Norway from 1,800 known cases in 1875 to just 575 cases in 1901. Hansen had had syphilis since the 1860s but died of heart disease. He was an atheist. [10] [11]