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End plate potentials (EPPs) are the voltages which cause depolarization of skeletal muscle fibers caused by neurotransmitters binding to the postsynaptic membrane in the neuromuscular junction. They are called "end plates" because the postsynaptic terminals of muscle fibers have a large, saucer-like appearance.
The shape of a distribution will fall somewhere in a continuum where a flat distribution might be considered central and where types of departure from this include: mounded (or unimodal), U-shaped, J-shaped, reverse-J shaped and multi-modal. [1]
The aggregate sum of many MEPPs is an end plate potential (EPP). A normal end plate potential usually causes the postsynaptic neuron to reach its threshold of excitation and elicit an action potential. [1] Electrical synapses do not use quantal neurotransmitter release and instead use gap junctions between neurons to send current flows between ...
A Pearson density p is defined to be any valid solution to the differential equation (cf. Pearson 1895, p. 381) ′ () + + + + = ()with: =, = = +, =. According to Ord, [3] Pearson devised the underlying form of Equation (1) on the basis of, firstly, the formula for the derivative of the logarithm of the density function of the normal distribution (which gives a linear function) and, secondly ...
where is the beta function, is the location parameter, > is the scale parameter, < < is the skewness parameter, and > and > are the parameters that control the kurtosis. and are not parameters, but functions of the other parameters that are used here to scale or shift the distribution appropriately to match the various parameterizations of this distribution.
where S X is the skewness of X and is the standard deviation of X. It follows that the sum of two random variables can be skewed (S X+Y ≠ 0) even if both random variables have zero skew in isolation (S X = 0 and S Y = 0). The standardized rank coskewness RS(X, Y, Z) satisfies the following properties: [4]
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The formula for a finite sample is [28] = + + () where n is the number of items in the sample, g is the sample skewness and k is the sample excess kurtosis. The value of b for the uniform distribution is 5/9. This is also its value for the exponential distribution.