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The number of cases of puerperal sepsis per year shows wide variations among published literature—this may be related to different definitions, recordings etc. [12] Globally, bacterial infections are the cause of 10% of maternal deaths—this is more common in low income countries but is also a direct cause of maternal deaths in high-income ...
Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) (such as meningitis, pneumonia, pyelonephritis, or gastroenteritis) in the setting of fever. Older textbooks may refer to neonatal sepsis as "sepsis neonatorum".
Prematurity, low birth weight, chorioamnionitis, maternal urinary tract infection and/or maternal fever are complications that increase the risk for early-onset sepsis. Early onset sepsis is indicated by serious respiratory symptoms. The infant usually develops pneumonia, hypothermia, or shock. The mortality rate is 30 to 50%. [30]
Vienna General Hospital in 1784. Semmelweis worked at the maternity clinic. Copper engraving by Josef & Peter Schafer. Historically, puerperal fever was a devastating disease. It affected women within the first three days after childbirth and progressed rapidly, causing acute symptoms of severe abdominal pain, fever and debility.
Modifiable risk factors include maternal obesity. [14] There is an elevated demand for insulin during pregnancy which leads to increased insulin production from pancreatic beta cells. The elevated demand is a result of increased maternal calorie intake and weight gain, and increased production of prolactin and growth hormone.
Sepsis is defined as SIRS in response to an infectious process. [49] Severe sepsis is defined as sepsis with sepsis-induced organ dysfunction or tissue hypoperfusion (manifesting as hypotension, elevated lactate, or decreased urine output). Severe sepsis is an infectious disease state associated with multiple organ dysfunction syndrome (MODS) [9]
The UNCoLSC therefore works to make these thirteen life-saving commodities more widely available and used in low-income nations to forestall preventable maternal and children deaths. [1] These thirteen commodities are below with the common barriers or medical conditions that they prevent or help in parentheses: [2] Oxytocin - (postpartum ...
For infants who are infected by their mothers before birth, two potential adverse scenarios exist: Generalized infection may occur in the infant, and can cause complications such as low birth weight, microcephaly, seizures, petechial rash similar to the "blueberry muffin" rash of congenital rubella syndrome, and moderate hepatosplenomegaly (with jaundice).