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Interneurons (also called internuncial neurons, association neurons, connector neurons, or intermediate neurons) are neurons that are not specifically motor neurons or sensory neurons. Interneurons are the central nodes of neural circuits , enabling communication between sensory or motor neurons and the central nervous system (CNS). [ 2 ]
CA3 has been implicated in a number of working theories on memory and hippocampal learning processes. Slow oscillatory rhythms (theta-band; 3–8 Hz) are cholinergically driven patterns that depend on coupling of interneurons and pyramidal cell axons via gap junctions, as well as glutaminergic (excitatory) and GABAergic (inhibitory) synapses.
A multipolar neuron is a type of neuron that possesses a single axon and many dendrites (and dendritic branches), allowing for the integration of a great deal of information from other neurons.
Cortical interneurons only make up around a fifth of the neuronal population but they play a major role in modulating cortical activity needed for cognition and many aspects of learning and memory. Cortical interneurons vary in shape, molecular make-up, and electrophysiology; they function collectively to maintain the balance between excitation ...
While at Harvard, a place where psychology was dominated by the work of B. F. Skinner, Kandel became interested in learning and memory. However, while Skinner championed a strict separation of psychology, as its own level of discourse, from biological considerations such as neurology, Kandel's work is essentially centered on an explanation of ...
At the same time, they are inhibited by dendritic synapses from the interneurons of the VMGB. This type of synaptic nesting is characteristic of other regions in the thalamus as well. Intrathalamic Interneurons: These interneurons provide inhibitory input to the relay cells at the synaptic nests. The target of their axons however, is not clear.
First proposed in 1965 by Ronald Melzack and Patrick Wall, the theory offers a physiological explanation for the previously observed effect of psychology on pain perception. Combining early concepts derived from the specificity theory and the peripheral pattern theory , the gate control theory is considered to be one of the most influential ...
Basket cells are multipolar GABAergic interneurons that function to make inhibitory synapses and control the overall potentials of target cells. In general, dendrites of basket cells are free branching, contain smooth spines, and extend from 3 to 9 mm. Axons are highly branched, ranging in total from 20 to 50mm in total length.